The best month to fly between Amsterdam and Istanbul is March and the most expensive month to fly is July. (Average prices, based on 1130 datapoints.)
The best day to arrive at Amsterdam is Monday and it would be best to avoid Friday, as prices are on average 69.27% higher than on Monday. (Average prices, based on 1132 datapoints.)
The best time to fly is at around 7. (Average prices, based on 2073 datapoints.)