Flight Guarulhos International Airport departs from Sao Paulo Guarulhos International Airport at 21:30 and arrives at New York Newark Liberty International Airport at 05:20.
The flighttime is about 8h 50m. The distance travelled ("as the bird flies"): 4312 Km. So the average speed is roughly 488 Km.
There is an 1 hour time difference between Sao Paulo and New York