Flight Adolfo Suárez Madrid–Barajas Airport departs from Madrid Adolfo Suárez Madrid–Barajas Airport at 23:55 and arrives at Sao Paulo Guarulhos International Airport at 05:25.
The flighttime is about 10h 30m. The distance travelled ("as the bird flies"): 7748 Km. So the average speed is roughly 738 Km.
There is an 5 hour time difference between Madrid and Sao Paulo