Please be aware that Osaka and Tokyo has multiple airports and that these results are for all airports serving the city.
The best month to fly between Osaka and Tokyo is August and the most expensive month to fly is July. (Average prices, based on 3793 datapoints.)
The best day to arrive at Osaka is Tuesday and it would be best to avoid Saturday, as prices are on average 7.7% higher than on Tuesday. (Average prices, based on 3420 datapoints.)
The cheapest airline flying from Osaka to Tokyo is Peach Aviation. They are 61% cheaper than Japan Airlines. (Average prices, based on 3803 datapoints.)
The best time to fly is at around 10. (Average prices, based on 6952 datapoints.)