Flight Tocumen International Airport departs from Panama City Tocumen International Airport at 21:25 and arrives at Havana José Marti International Airport at 00:01.
The flighttime is about 1h 36m. The distance travelled ("as the bird flies"): 414 Km. So the average speed is roughly 259 Km.
There is an 1 hour time difference between Panama City and Havana