Flight Istanbul Atatürk Airport departs from Istanbul Istanbul Atatürk Airport at 21:50 and arrives at Rome Leonardo da Vinci–Fiumicino Airport at 23:30.
The flighttime is about 2h 40m. The distance travelled ("as the bird flies"): 1844 Km. So the average speed is roughly 692 Km.
There is an 1 hour time difference between Istanbul and Rome