Flight La Guardia Airport departs from New York La Guardia Airport at 06:15 and arrives at San Diego International Airport at 18:33.The flight has a short stop at San Francisco. The flighttime is about 15h 18m. The distance travelled ("as the bird flies"): 4805 Km. So the average speed is roughly 314 Km. There is an 3 hour time difference between New York and San Diego