Flight International Airport departs from San Diego International Airport at 10:17 and arrives at Chicago O'Hare International Airport at 06:25.The flight has a short stop at New York.
The flighttime is about 18h 08m. The distance travelled ("as the bird flies"): 3253 Km. So the average speed is roughly 179 Km.
There is an 2 hour time difference between San Diego and Chicago