Flight International Airport departs from San Francisco International Airport at 09:10 and arrives at Chicago O'Hare International Airport at 22:45.The flight has a short stop at New York.
The flighttime is about 11h 35m. The distance travelled ("as the bird flies"): 3832 Km. So the average speed is roughly 331 Km.
There is an 2 hour time difference between San Francisco and Chicago